RNA sequencing of mammary glands from 55-day old control, MTB-200ba429, MTB-IGFIR, MTB-IGFIRba429 mice.

RNA was isolated from mammary glands from 55 day old control mice, mice overexpressing the miR-200b/200a/429 cluster in mammary epithelial cells (MTB-200ba429) mice overexpressing the IGF-IR transgene in mammary epithelial cells (MTB-IGFIR), and mice overexpressing both the miR-200b/200a/429 cluster and the IGF-IR transgene in mammary epithelial cells (MTB-IGFIRba429) 4 control, 4 MTB-200ba429, 4 MTB-IGFIR and 3 MTB-IGFIRba429 samples

本研究从55日龄对照小鼠、乳腺上皮细胞特异性过表达miR-200b/200a/429基因簇（miR-200b/200a/429 cluster）的转基因小鼠（MTB-200ba429）、乳腺上皮细胞特异性过表达胰岛素样生长因子1受体（IGF-IR）转基因的小鼠（MTB-IGFIR），以及同时在乳腺上皮细胞中特异性过表达miR-200b/200a/429基因簇与IGF-IR转基因的小鼠（MTB-IGFIRba429）的乳腺组织中分离RNA；各组样本量依次为4例对照、4例MTB-200ba429样本、4例MTB-IGFIR样本及3例MTB-IGFIRba429样本。