Dyslipidemia in Adolescents Seen in a University Hospital in the city of Rio de Janeiro/Brazil: Prevalence and Association

Abstract Background: Early exposure to obesity favors greater risks of cardiovascular factors such as dyslipidemia. Objectives: To establish the prevalence of dyslipidemia, and to evaluate its association with nutritional status of the adolescents attended at the ambulatory of the Adolescent Health Studies Center of the University Hospital Pedro Ernesto. Methods: This is a cross-sectional, observational study, the sample of which was of convenience, consisting of adolescents from 12 to 18 years old of both genders. The lipid profile was evaluated, along with its association with the anthropometric indicators: body mass index and waist circumference. For statistical analysis, a significance level of 5% was used. Results: A total of 239 adolescents, 104 boys (43.5%) and 135 girls (56.5%) were evaluated and, of these, 52 (21.8%) were eutrophic, 60 (25.1%) overweight, and 127 (53.1%) obese. Obeseadolescents had significantly lower mean values of HDL-cholesterol (44.7 mg/dl vs 53.9 mg/dl; p

摘要背景：早年暴露于肥胖状态会显著升高血脂异常（dyslipidemia）等心血管危险因素的患病风险。
研究目的：明确佩德罗·埃内斯托大学医院青少年健康研究中心门诊就诊青少年的血脂异常患病率，并评估其与该人群营养状况的关联。
研究方法：本研究为横断面观察性研究（cross-sectional observational study），采用便利抽样（convenience sampling）法，纳入12~18岁的男女青少年。检测所有受试者的血脂谱，并分析其与体质量指数（body mass index, BMI）、腰围等人体测量学指标的关联。统计学分析采用5%的显著性检验水准。
研究结果：共纳入239名青少年，其中男性104名（43.5%），女性135名（56.5%）。受试者中，营养正常者52名（21.8%），超重者60名（25.1%），肥胖者127名（53.1%）。肥胖青少年的高密度脂蛋白胆固醇（HDL-cholesterol）平均水平显著低于非肥胖青少年（44.7 mg/dl vs 53.9 mg/dl；p