A detailed ultrastructural examination of lung cryobiopsy samples from a COVID-19 patient case series – Data set 07

We investigated six cryobiopsy samples from six deceased patients (patients C03 to C08 from Barisione et al. 2020 doi.org/10.1007/s00428-020-02934-1) by using thin section electron microscopy (Cortese et al. 2022 doi.org/10.1007/s00428-022-03308-5). A detailed description of the methods and the data set is provided in the download container. Data set 07 contains stitched image montages of thin sections (selected areas) through the lung of patients C04 to C06 which were acquired by scanning electron microscopy. The images show alveolae with different degree of structural modification: Intact alveolar septum (C06); alveolar septum with detached alveolar epithelium (C04); dissolved alveolar organization (C05).本研究采用超薄切片电子显微镜（thin section electron microscopy）技术，对6名已故患者的6份冷冻活检（cryobiopsy）样本开展分析，患者编号为C03至C08，相关数据源自Barisione等人2020年的研究（DOI: 10.1007/s00428-020-02934-1）；本研究的实验方法参考了Cortese等人2022年的研究（DOI: 10.1007/s00428-022-03308-5）。数据集与实验方法的详细说明已在下载资源包中提供。数据集07包含经扫描电子显微镜（scanning electron microscopy）采集的、对应患者C04至C06肺部的超薄切片（选定区域）拼接全景图像。这些图像展示了不同结构损伤程度的肺泡：完整肺泡隔（C06）、伴肺泡上皮脱离的肺泡隔（C04）以及肺泡组织结构溶解（C05）。