Suppression of multiple genotypes by sup-35.

All experiments performed at 20��C unless indicated. Experiments involving lin-35 and ubc-18 were performed using the alleles n745 and ku354, respectively. We note that pharyngeal morphology and function was normal in the suppressed fertile adults.aDouble mutants were derived from a parental strain carrying the lin-35-rescuing extrachromosomal array, kuEx119.bDouble mutants were maintained by propagating low-frequency escapers of the synthetic lethality.

除非另有说明，所有实验均在20摄氏度条件下进行。涉及lin-35与ubc-18的实验，分别采用等位基因n745和ku354完成。需说明的是，经挽救的可育成虫的咽部形态与功能均表现正常。
a 双突变体源自携带可挽救lin-35功能的染色体外阵列kuEx119的亲本菌株。
b 双突变体通过传代合成致死表型的低频逃逸个体进行维持。