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Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells

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Organisation for Economic Co-operation and Development2026-04-11 收录
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https://www.oecd.org/en/publications/test-no-479-genetic-toxicology-in-vitro-sister-chromatid-exchange-assay-in-mammalian-cells_9789264071384-en.html
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The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...

姐妹染色单体互换(sister chromatid exchange,SCE)检测法是一种用于检测复制中染色体的两条姐妹染色单体之间DNA相互交换事件的短期检测手段。对SCE的检测需借助特定方法对姐妹染色单体进行差异标记……
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