GNPS - Purine metabolism modulates leukemia stem cell maintenance in MLL-rearranged acute leukemia

The metabolomics analysis of leukemia stem cells with or without drug treatment was performed using an ion chromatography mass spectrometer or a QExactive HF-X hybrid quadrupole orbitrap high-resolution mass spectrometer.

本研究针对经药物处理与未经过药物处理的白血病干细胞（leukemia stem cells），采用离子色谱-质谱联用仪（ion chromatography mass spectrometer）或QExactive HF-X混合型四极杆-轨道阱高分辨质谱仪（QExactive HF-X hybrid quadrupole orbitrap high-resolution mass spectrometer）开展代谢组学分析。