Muscle strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans. Muscle strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans

Traumatic strain injury in skeletal muscle is often associated with fluid accumulation on the site of rupture, but the role of this injury exudate in cellular responses and healing is unknown. Exudate fluid from subjects suffering from acute hamstering or calf muscle strain injury was aspirated and the cells isolated. These exudate cells and cells derived from the blood were subjected to RNA sequencing and compared to analyze the nature of the exudate cells. Overall design: Comparison of exudate and blood derived cells from four subjects.

骨骼肌创伤性拉伤常伴随破裂部位体液积聚，但该损伤渗出液在细胞应答与创伤愈合中的作用尚不明确。本研究对罹患急性腘绳肌或小腿肌肉拉伤的受试者采集其损伤渗出液并分离其中的细胞；对上述渗出液来源细胞及血液来源细胞进行RNA测序，并通过组间比较分析渗出液细胞的生物学特性。实验设计：对比4名受试者的渗出液来源细胞与血液来源细胞。