Reduced SCRIB expression compromises endometrial stromal cells decidualization. Reduced SCRIB expression compromises endometrial stromal cells decidualization

To identify the molecular pathway regulated by Scribble (SCRIB) in primary hunan endometrial stromal cells (ESCs) decidualization, high-throughput RNA-seq was performed to analyze the transcriptome profile in si-Ctrl or si-SCRIB transfected decidualized ESCs (dESCs). Overall design: mRNA profiles of si-Ctrl or si-SCRIB tranfected dESCs.

为鉴定Scribble（SCRIB）在原代人子宫内膜基质细胞（endometrial stromal cells, ESCs）蜕膜化过程中的调控分子通路，本研究采用高通量RNA测序（high-throughput RNA-seq）技术，分析了转染si-Ctrl或si-SCRIB的蜕膜化ESCs（dESCs）的转录组谱。实验整体设计：转染si-Ctrl或si-SCRIB的蜕膜化ESCs的mRNA表达谱。