MEF to iPSC reprogramming - Serum condition

scRNA-seq time-series dataset of mouse embryonic fibroblast (MEF) reprogramming to induced pluripotent stem cells (iPSCs) subsetted to the serum condition and assayed using 10x Genomics. Contains 39 time points spanning days 0-18 during reprogramming. Total cell number is 165,892. Note that this dataset has already been normalized by total counts and log-transformed. We added the `cell_sets` annotation by slightly modifying and combining the pre-computed annotations, introducing a `MEF/other` category that didn't exist in the original data. <br> Please cite the original publication: https://doi.org/10.1016/j.cell.2019.01.006

本数据集为小鼠胚胎成纤维细胞（mouse embryonic fibroblast, MEF）重编程为诱导多能干细胞（induced pluripotent stem cells, iPSCs）的单细胞RNA测序（single-cell RNA sequencing, scRNA-seq）时间序列数据集，筛选得到血清培养条件下的样本，并通过10x Genomics平台完成检测。该数据集涵盖重编程过程中0至18天的39个时间点，总细胞数达165892。请注意，本数据集已通过总计数标准化并完成对数转换。我们通过轻度修改并整合预计算注释的方式，新增了`cell_sets`注释，并引入了原数据中未包含的`MEF/other`分类。请引用原始文献：https://doi.org/10.1016/j.cell.2019.01.006