Neuron Morphology data in .swc format from Patch-seq experiments in mouse cortex, Cell ID 711770582

Mouse cortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of mouse cortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).

小鼠皮层神经元展现出多样化的形态学特征、生理学特性与基因表达谱。本研究采用膜片钳测序（Patch-seq）技术，该方法可从同一神经元中同时获取三种数据模态，旨在阐明小鼠皮层神经元类型的遗传特征与其形态学及电生理表型之间的对应关系。本数据集包含以下类型的文件：图像栈（TIFF格式）、图像空间重建文件（.swc，单位：µm）、经坐标转换的重建文件（.swc，单位：µm，其y轴垂直向上指向软脑膜表面），以及标记文件（.marker，单位：µm）。该标记文件用于标注三类节点：树突被截断的节点（代码10）、重建未继续的节点（代码20），以及组织表面最贴近胞体的节点（代码30）。