SIGN 50 Checklist for RCT Study Design.

Note that only the RCT in Table 2 was assessed across all quality criteria in SIGN 50. For all CCT study designs in Tables 3 and 4, only criteria 1.1 appeared relevant to the focus of the study and therefore only scored for that criterion. See limitations section of the manuscript for a description of this challenge.
SIGN 50 Network: A Guideline Developer’s Handbook http://www.sign.ac.uk/guidelines/fulltext/50/checklist2.html

请注意，仅表2中的随机对照试验（Randomized Controlled Trial, RCT）按照SIGN 50的全部质量标准完成了评估。针对表3与表4中的所有临床对照试验（Controlled Clinical Trial, CCT）研究设计，仅标准1.1与本研究的核心主题相关，故仅针对该标准进行质量评分。有关该研究难点的详细说明，请参阅本文手稿的局限性章节。
《SIGN 50：指南制定者手册》：http://www.sign.ac.uk/guidelines/fulltext/50/checklist2.html