METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin

This study aims to determine the efficacy, safety, and tolerability of the sequential addition of immune-modulating therapy to standard-of-care therapy of microsatellite-stable (MSS)/mismatch repair-proficient (pMMR) metastatic colorectal cancer (mCRC).

本研究旨在明确在微卫星稳定（microsatellite-stable, MSS）/错配修复功能完整（mismatch repair-proficient, pMMR）转移性结直肠癌（metastatic colorectal cancer, mCRC）的标准治疗方案中序贯添加免疫调节治疗的疗效、安全性与耐受性。