Most relevant biological networks identified for common genes.

The list of biological networks was generated using the Analyze Networks (AN) algorithm with default settings (MetaCore), based on relative enrichment with the uploaded data and the relative saturation of networks with canonical pathways.P-value: represents the probability for a particular mapping of an experiment to a map (or network, or process) to arise by chance considering the number of genes in the experiment versus the number of genes in the map within the “full set” of all genes on maps. Z-score ranks the sub-networks of the AN algorithm with regard to their saturation with genes from the experiment.Most relevant biological networks identified for common genes.

本研究生成的生物学网络列表，依托MetaCore平台，采用分析网络（Analyze Networks，AN）算法并以默认参数配置完成，构建依据为上传数据的相对富集水平，以及网络与经典通路的相对饱和程度。P值（P-value）：指在所有图谱的全基因集合中，对比实验基因总数与单张图谱内基因总数时，某次实验与某张图谱（或网络、生物学过程）的特定映射关系偶然发生的概率。Z得分（Z-score）可依据子网络被实验基因覆盖的饱和程度，对AN算法生成的子网络进行排序。本次分析得到针对共有基因的最具生物学相关性的网络集合。