Fear conditioning - Days 1 - 3

This dataset contains single cell calcium imaging recordings of D1- and D2-MSNs in the nucleus accumbens shell of freely-moving mice during an appetitive and aversive Pavlovian conditioning protocol. The data was collected using one-photon microscopy and processed with CaImAn and IDPS software. The data can be used to study the differential response of D1- and D2-MSNs to conditioned stimulus (e.g. predictive cues) and unconditioned stimuli (e.g. sucrose, condensed milk, tail lift and foot-shock). Read the "metadata" files for more information.

本数据集包含自由活动小鼠伏隔核壳区（nucleus accumbens shell）内D1型与D2型中型多棘神经元（Medium Spiny Neurons, MSNs）的单细胞钙成像记录，实验采用了奖赏性与厌恶性巴甫洛夫条件化范式。该数据集通过单光子显微镜（one-photon microscopy）采集，并使用CaImAn与IDPS软件完成数据处理。本数据集可用于研究D1型与D2型中型多棘神经元对条件刺激（conditioned stimulus，如预测性线索）与非条件刺激（unconditioned stimuli，如蔗糖、炼乳、尾部提拉刺激及足部电击）的差异化响应。详细信息请查阅“元数据（metadata）”文件。