Data_Sheet_1_Facilitating Word Retrieval in Aphasia: Which Type of Cues for Which Aphasic Speakers?.docx

Background: Even if both phonological and semantic cues can facilitate word retrieval in aphasia, it remains unclear if their respective effectiveness varies according to the underlying anomic profile.
Aim: The aim of the present facilitation study is to compare the effect of phonological and semantic cues on picture naming accuracy and speed in different types of anomia.
Methods: In the present within-subject design study, 15 aphasic persons following brain damage underwent picture naming paradigms with semantic cues (categorically- or associatively related) and phonological cues (initial phoneme presented auditorily, visually or both).
Results: At the group level, semantic cueing was as effective as phonological cueing to significantly speed up picture naming. However, while phonological cues were effective regardless of the anomic profile, semantic cueing effects varied depending on the type of anomia. Participants with mixed anomia showed facilitation after both semantic categorical and associative cues, but individuals with lexical-phonological anomia only after categorical cues. Crucially, semantic cues were ineffective for participants with lexical-semantic anomia. These disparities were confirmed by categorical semantic facilitation decreasing when semantic/omission errors prevailed in the anomic profile, but increasing alongside phonological errors.
Conclusion: The effectiveness of phonological vs semantic cues seems related to the underlying anomic profile: phonological cues benefit any type of anomia, but semantic cues only lexical-phonological or mixed anomia.

背景：尽管语音线索（phonological cue）与语义线索（semantic cue）均可促进失语症（aphasia）患者的词汇提取，但二者的有效性是否会根据患者潜在的命名障碍特征（anomic profile）产生差异，目前尚无定论。
目的：本促进性研究旨在对比语音线索与语义线索对不同类型命名障碍（anomia）患者图片命名准确性与速度的影响。
方法：本研究采用被试内实验设计，纳入15名脑损伤后失语症患者，让其完成两类线索条件下的图片命名任务：语义线索（分为类别相关与联想相关两类）与语音线索（分别通过听觉、视觉或双通道呈示首音素）。
结果：在群体水平上，语义线索提示与语音线索提示均可显著加快图片命名速度，且二者的有效程度相当。但语音线索的有效性不受命名障碍特征的影响，而语义线索提示的效果则随命名障碍类型的不同而存在差异：混合性命名障碍患者在接受类别相关与联想相关两类语义线索提示后均表现出促进效应；词汇-语音型命名障碍患者仅在类别相关语义线索提示下出现促进效应；尤为关键的是，词汇-语义型命名障碍患者无法从语义线索提示中获益。上述差异得到了进一步验证：当命名障碍特征以语义错误/遗漏错误为主时，类别相关语义线索的促进效应会减弱；而当错误类型以语音错误为主时，该促进效应则会增强。
结论：语音线索与语义线索提示的有效性似乎与患者潜在的命名障碍特征密切相关：语音线索可使所有类型的命名障碍患者获益，而语义线索仅对词汇-语音型或混合性命名障碍患者有效。