HEB associates with PRC2 and SMAD2/3 to regulate developmental fates [RNA-Seq]. Mus musculus

We report the interaction between HEB and PRC2 components in mouse embryonic stem cells (ESCs) Overall design: We profiled gene expression for biological triplicate shControl- and shHEB-infected ESCs and differentiated embryoid body (EB) in serum-free defined culture system with or without activin treatment

本研究报道了小鼠胚胎干细胞（ESCs）中HEB与多梳抑制复合体2（PRC2）复合物组分之间的相互作用。
整体实验设计：本研究对三组生物学重复的经sh对照慢病毒及靶向HEB的短发夹RNA慢病毒感染的小鼠胚胎干细胞，以及在添加或不添加激活素的无血清限定培养体系中诱导分化得到的拟胚体（EB）进行了基因表达谱分析。