[Dataset] Comparative analysis of 1H NMR and 1H–13C HSQC NMR metabolomics to understand the effects of medium composition in yeast growth

NMR datasets used in https://doi.org/10.1021/acs.analchem.8b01196. In the corresponding study, we have performed a comparative chemometric analysis between untargeted 1H NMR and 1H-13C HSQC NMR analyses of metabolomics samples from Saccharomyces cerevisiae (yeast) extracts. Specifically, yeast was grown in two different liquid media and their metabolism was characterized at 8 different time-points of a 3-day period. The two media used, YPD (Yeast Peptone Dextrose) and YSC (Yeast nitrogen base Synthetic Complete), are broadly used in yeast lab routines, and results from this analysis should be of interest for improving lab methodologies involving yeast.

用于https://doi.org/10.1021/acs.analchem.8b01196的核磁共振（NMR）数据集。在对应的研究中，我们对酿酒酵母（Saccharomyces cerevisiae，酵母）提取物的代谢组学样本进行了非靶向1H NMR与1H-13C HSQC NMR分析的比较化学计量学研究。具体而言，酵母在两种不同的液体培养基中培养，并在3天周期内的8个不同时间点对其代谢特征进行了表征。所用的两种培养基为YPD（Yeast Peptone Dextrose，酵母蛋白胨葡萄糖培养基）和YSC（Yeast nitrogen base Synthetic Complete，酵母氮源合成完全培养基），二者广泛应用于酵母实验室常规操作；本分析结果或可为改进涉及酵母的实验室方法学提供参考。