Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation

The purpose of this study is to evaluate the efficacy and safety of naldemedine in the treatment of opioid-induced constipation (OIC) in adults with non-malignant chronic pain who are not using laxatives.本研究旨在评估纳地美定（naldemedine）用于治疗未使用泻药的非恶性慢性疼痛成年患者的阿片类药物诱导性便秘（OIC）的疗效与安全性。