Demographic and clinical characteristics of HCs, CIS patients, all MS patients and MS subtypes patients.

Data are expressed as median and range (in brackets). There were no statistically significant differences between HCs and MS patients in age (p = 0.721; 0.153) or sex (p = 0.148; 0.332). § Mann-Whitney U test between CIS and MS patients. * Kruskal Wallis one-way analysis of variance among MS patients.HCs = healthy controls subjects; CIS = clinically isolated syndrome; MS = multiple sclerosis; MS Subtypes: RR = relapse remitting; SP = secondary progressive, PP = primary progressive.

数据以中位数及范围（括号内标注）形式呈现。健康对照者（healthy controls, HCs）与多发性硬化（multiple sclerosis, MS）患者在年龄（p = 0.721；0.153）或性别（p = 0.148；0.332）方面均无统计学显著性差异。§ 临床孤立综合征（clinically isolated syndrome, CIS）与MS患者间采用曼-惠特尼U检验；* MS患者组内采用克罗斯卡尔-沃利斯单因素方差分析。MS亚型：RR为复发缓解型；SP为继发进展型；PP为原发进展型。