Differential Expression of MicroRNAs Among Cell Populations in the Regenerating Adult Mouse Olfactory Epithelium

Progenitor cells were purified from methimazole-lesioned olfactory epithelium based on c-Kit expression, and miRNA expression was assayed in c-Kit (+) and c-Kit (-) cell populations. Progenitor cells were purified from methimazole-lesioned olfactory epithelium based on c-Kit expression, and miRNA expression was assayed in c-Kit (+) and c-Kit (-) cell populations. N=3 mice/samples per group.

研究人员基于c-Kit表达，从甲巯咪唑损伤的嗅上皮中分离纯化祖细胞 (Progenitor cells)，并对c-Kit阳性（c-Kit (+)）与c-Kit阴性（c-Kit (-)）细胞群体的微小RNA (miRNA) 表达水平进行了检测。研究人员基于c-Kit表达，从甲巯咪唑损伤的嗅上皮中分离纯化祖细胞 (Progenitor cells)，并对c-Kit阳性（c-Kit (+)）与c-Kit阴性（c-Kit (-)）细胞群体的微小RNA (miRNA) 表达水平进行了检测。每组设置3只小鼠/样本。