Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds

An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo[3.2.1]octanoid scaffolds will be described.本研究已开发出一套自动化硅基微反应器系统，可用于开展快速、小体积的多维度反应筛选。本文将阐述如何利用该微流控平台，对多官能团化双环[3.2.1]辛烷类(bicyclo[3.2.1]octanoid)母核的转化反应进行识别与鉴定。