Additional file 2 of Long-term environmental metal exposure is associated with hypomethylation of CpG sites in NFKB1 and other genes related to oncogenesis
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Additional file 2: Additional spreadsheets present information about positions and regions of DMPs and conversion rate and raw read numbers for each sample included in the current study (Additional spreadsheets 1 and 2, respectively). Further, this file contains the results of differential methylation analysis, DMPs associated with chemical elements blood levels as well as CpGs associated with elements concentration obtained by linear regression analysis adjusted for gender, age, BMI class, smoking and each element separately (Additional spreadsheets 3, 4 and 5, respectively).
附加文件2:内含的附加电子表格提供了本研究纳入的所有样本的差异甲基化位点(Differentially Methylated Positions, DMPs)的位置与区域信息,以及各样本的转化率和原始读段数,两类信息分别对应附加电子表格1和附加电子表格2。此外,该文件还包含差异甲基化分析结果、与血液化学元素水平相关的DMPs,以及通过校正性别、年龄、BMI分级、吸烟状况及各单独待测元素的线性回归分析得到的与元素浓度相关的CpG位点(CpG sites, CpGs)的相关结果,三类结果分别对应附加电子表格3、4和5。
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figshare
创建时间:
2023-08-08



