Data from: Mapping of Dynamic Transcriptome Changes Associated with Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse.

The dataset contains six files of tabular data with an accompanying README file.

Supplementary file 1: Customized probe annotation file for the Nanostring nCounter Mouse PanCancer Immune Profiling Panel (catalog # 115000142). This file is provided as supporting material for a journal article. Codes for columns are in file.

Supplementary file 2: Microsoft Excel document with output from nSolver for differential expression analyses for pairwise comparisons noted by each named sheet. This data set is supporting material for a journal article. Codes for columns are listed in README.

Supplementary File 3: Microsoft Excel document with output from nSolver for global and directed significance scores for immune pathways. This data set is supporting material for a journal article.

Supplementary File 4: Microsoft Excel document with output from nSolver for immune pathway Z scores for pairwise comparisons noted by each named sheet (11 sheets total). This data set is supporting material for a journal article.

Supplementary File 5: Microsoft Excel document with output from nSolver for cell type profiling scores for VEH vs cSiO2 exposed mice, as noted by each tab name (8 sheets total). This data set is supporting material for a journal article.

Supplementary File 6: Microsoft Excel document with protein networks obtained from STRING database and clusters predicted by the MCL algorithm. This data set is supporting material for a journal article. File contains 14 sheets. Descriptions for columns of the "network" sheets are in the README file

本数据集包含6个表格数据文件及1份配套的README文件。

补充文件1：针对Nanostring nCounter 小鼠泛癌免疫分析面板（Nanostring nCounter Mouse PanCancer Immune Profiling Panel，货号：115000142）的定制化探针注释文件。本文件作为期刊论文的配套支撑材料提供，列编码规则详见该文件内部。

补充文件2：包含nSolver差异表达分析结果的Microsoft Excel文档，各工作表命名对应其所标注的两两比较组。本数据集为期刊论文配套支撑材料，列编码规则详见README文件。

补充文件3：包含nSolver分析得到的免疫通路全局及定向显著性评分结果的Microsoft Excel文档，本数据集为期刊论文配套支撑材料。

补充文件4：包含nSolver分析得到的免疫通路Z评分结果的Microsoft Excel文档，各工作表命名对应其所标注的两两比较组（共含11个工作表），本数据集为期刊论文配套支撑材料。

补充文件5：包含nSolver分析得到的VEH与cSiO₂暴露小鼠的细胞类型分型评分结果的Microsoft Excel文档，各工作表命名对应其所标注的实验组（共含8个工作表），本数据集为期刊论文配套支撑材料。

补充文件6：包含从STRING数据库获取的蛋白质互作网络及由马尔可夫聚类算法（Markov Cluster Algorithm, MCL）预测得到的聚类结果的Microsoft Excel文档，本数据集为期刊论文配套支撑材料。该文件共包含14个工作表，"network"工作表的列描述详见README文件。