Additional file 4: Table S2. of Immunosenescence of the CD8+ T cell compartment is associated with HIV-infection, but only weakly reflects age-related processes of adipose tissue, metabolism, and muscle in antiretroviral therapy-treated HIV-infected patients and controls

Unadjusted and adjusted associations between CD8+ T cell subset sizes and ageing parameters in HIV+. Adjusted analyses are in grey. Age was adjusted for HIV-duration, ART-duration, and current ART; IL-6, suPAR, HOMA-IR, metabolic syndrome, VAT, and lLMI were adjusted for age, HIV-duration, ART-duration, and current ART. †Parameters were transformed using log2(x). Estimates and confidence intervals are back transformed using (2β-1) × 100, and shown as percent change in the outcome per unit increase of the covariate. The bold values are statistically significant at *P

HIV阳性感染者体内CD8+ T细胞（CD8+ T cell）亚群比例与衰老相关参数之间的未校正与校正关联。校正分析结果以灰色字体呈现。针对年龄的校正分析中，纳入HIV感染时长、抗反转录病毒治疗（Antiretroviral Therapy, ART）时长及当前ART方案作为混杂因素；针对白细胞介素6（Interleukin 6, IL-6）、可溶性尿激酶型纤溶酶原激活物受体（soluble urokinase-type plasminogen activator receptor, suPAR）、胰岛素抵抗稳态模型评估（Homeostatic Model Assessment for Insulin Resistance, HOMA-IR）、代谢综合征、内脏脂肪组织（Visceral Adipose Tissue, VAT）与肢体瘦体重指数（lLMI）的校正分析中，则纳入年龄、HIV感染时长、ART时长及当前ART方案作为混杂因素。† 所有参数均通过log₂(x)进行对数转换。效应估计值与置信区间将通过(2β - 1)×100进行逆变换，并以每单位协变量增加时结局指标的百分比变化形式展示。标粗数值代表具有统计学显著性，*P