Gene level network analysis of transcriptome changes in lymphoblastoid cell lines derived from C9ORF72-ALS cases.

WGCNA analysis identified nine gene networks which were dysregulated between C9ORF72-ALS and control samples. The median fold change of genes within each network and the functional enrichment of each of the gene networks is tabulated. A fold change of >1 equates to up-regulation and a fold change of <1 equates to down-regulation.
Gene level network analysis of transcriptome changes in lymphoblastoid cell lines derived from C9ORF72-ALS cases.

加权基因共表达网络分析（Weighted Gene Co-expression Network Analysis，WGCNA）鉴定出9个在C9ORF72相关肌萎缩侧索硬化症（C9ORF72-ALS）样本与对照样本间存在表达失调的基因共表达网络。各网络内基因的中位倍数变化值，以及各基因网络的功能富集分析结果均已制表汇总。其中，倍数变化值大于1代表基因上调，小于1则代表基因下调。
本数据集针对源自C9ORF72相关肌萎缩侧索硬化症患者的淋巴母细胞系（lymphoblastoid cell lines）的转录组（transcriptome）变化开展基因水平网络分析。