The performance of PremPS^M tested on eight datasets.

Here, the PremPS model was retrained after removing the overlapped mutations including their corresponding reverse mutations with each test set from the training set. The number of overlapped mutations is provided in the S1C Table.

本研究中，研究人员从训练集中移除了与各测试集存在重叠的突变及其对应的反向突变后，对PremPS模型进行了重新训练。重叠突变的数量详见S1C表格。