Influence of thiol connections on maintenance of glutathione in blood of judoists of high qualification

A question is considered about a place in the exchange of matters of glutathione, him general amount and picked up a thread form in blood of sportsmen. 18 sportsmen (eyelids - 18-24) which are on the stage of direct preparation to the competitions took part in research. Certainly, that before a basic experiment blood of sportsmen contained a few of general glutathione and him the picked up a thread form with antioxidant properties. For the correction of content of glutathione in blood were drawn on two metabolic complexes. The first complex contained amino acid-predecessors of glutathione. Second are predecessors of phosphocreatine. Sportsmen drew on complexes during three weeks. More effective influenced on the level of glutathione at blood of sportsmen of the use of amino acid - predecessors of glutathione. It is set that one of ways of correction of the state of the system of glutathione there is the use of sulfur-containing connections, including thiol antioxidants.

本研究围绕谷胱甘肽（glutathione）物质代谢相关问题，以及运动员血液中总谷胱甘肽及其巯基（thiol）形式的水平展开。本研究共纳入18名处于赛前直接备战阶段的运动员，年龄为18~24岁。实验前，受试者的血液中仅含有少量总谷胱甘肽及其具有抗氧化活性的巯基形式。为调节血液谷胱甘肽水平，研究设置了两种代谢复合补充剂：第一种复合补充剂包含谷胱甘肽的氨基酸前体（amino acid-predecessors），第二种则为磷酸肌酸（phosphocreatine）前体。运动员连续服用上述补充剂为期三周。结果显示，谷胱甘肽氨基酸前体补充剂对运动员血液谷胱甘肽水平的提升效果更为显著。研究证实，含硫化合物（包括巯基类抗氧化剂）是调节机体谷胱甘肽系统状态的有效途径之一。