Generation of KRAS signatures using immortalized isogenic lung cells.

We generated RNAseq profiles from Small Airway Epithelial Cells (SALE) expressing either KRAS G12V or GFP control. SALE stably expressing with KRAS G12V or GFP were harvested two weeks after infection.

本研究从分别表达KRAS G12V与绿色荧光蛋白（Green Fluorescent Protein, GFP）对照的小气道上皮细胞（Small Airway Epithelial Cells, SALE）中生成了RNA测序（RNA-seq）谱。感染后两周，收集稳定表达KRAS G12V或GFP的SALE细胞。