Coexistence of morphea and granuloma annulare: a rare case report

ABSTRACT CONTEXT: Localized scleroderma (morphea) is characterized by fibrosis of skin and subcutaneous tissue. Granuloma annulare is a relatively common disease that is characterized by dermal papules and arciform plaques. CASE REPORT: Here, we present the case of a 42-year-old woman who developed granuloma annulare on the dorsum of her feet and abdominal region, and morphea on the anterior side of her lower limbs. We also discuss the etiological and pathogenetic processes that may cause the rare coexistence of these two diseases. CONCLUSION: Only a few cases in the literature have described coexistence of morphea and granuloma annulare.

摘要背景：局限性硬皮病（morphea）以皮肤及皮下组织纤维化为特征。环状肉芽肿（Granuloma annulare）是一种较为常见的皮肤病，以真皮丘疹及弧形斑块为典型临床特征。
病例报告：本文报告1例42岁女性患者，其足背及腹部出现环状肉芽肿，下肢前侧出现硬斑病。本文并探讨了可能导致这两种疾病罕见共存的病因及发病机制。
结论：目前文献中仅报道过少数几例硬斑病与环状肉芽肿共存的病例。