ENZYMES AND METHODS FOR PRODUCING OMEGA-3 FATTY ACIDS

The present invention relates generally to the field of recombinant fatty acid synthesis， particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular， the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome， such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ. The present invention relates generally to the field of recombinant fatty acid synthesis， particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular， the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome， such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.

本发明总体涉及重组脂肪酸合成（recombinant fatty acid synthesis）领域，尤其聚焦于转基因植物（transgenic plants）方向。本申请阐明了参与脂肪酸合成的相关基因，并提供了用于调控植物油脂脂肪酸组成的方法与载体。具体而言，本发明提供了可将多种参与脂肪酸合成的异源基因（heterologous genes）整合至植物基因组的基因构建体，使得所得植株的多不饱和脂肪酸（polyunsaturated fatty acids）含量发生改变。本申请同时还披露了通过在植物贮藏器官（plant storage organ）中共表达沉默抑制子（silencing suppressor）以提升脂肪酸生物合成酶表达量的方法。
本发明总体涉及重组脂肪酸合成（recombinant fatty acid synthesis）领域，尤其聚焦于转基因植物（transgenic plants）方向。本申请阐明了参与脂肪酸合成的相关基因，并提供了用于调控植物油脂脂肪酸组成的方法与载体。具体而言，本发明提供了可将多种参与脂肪酸合成的异源基因（heterologous genes）整合至植物基因组的基因构建体，使得所得植株的多不饱和脂肪酸（polyunsaturated fatty acids）含量发生改变。本申请同时还披露了通过在植物贮藏器官（plant storage organ）中共表达沉默抑制子（silencing suppressor）以提升脂肪酸生物合成酶表达量的方法。