CircRNA sequencing data of tumors and paired adjacent tissue from HCC patients. CircRNA sequencing data of tumors and paired adjacent tissue from HCC patients

CircRNAs have emerged as crucial contributors to cancer progression. Nonetheless, the expression regulation, biological functions, and underlying mechanisms of circRNAs in mediating hepatocellular caicinoma(HCC) progression remain insuffuciently elucidated. In this study, we generated the circular RNA expression profile of HCC tissue together with the adjacent normal tissues by high-throughput RNA sequencing. Overall design: Circular RNA sequencing data of 5 tumors and paired adjacent tissues from HCC patients.

环状RNA（circRNAs）现已被证实为癌症进展的关键促成因素。然而，环状RNA在介导肝细胞癌（hepatocellular carcinoma, HCC）进展过程中的表达调控、生物学功能及潜在分子机制，仍未得到充分阐释。本研究通过高通量RNA测序（high-throughput RNA sequencing）技术，构建了肝细胞癌组织及其配对癌旁正常组织的环状RNA表达谱。实验整体设计：纳入5名肝细胞癌患者的5份肿瘤组织及其配对癌旁组织的环状RNA测序数据。