Intrauterine insemination: a UK survey on the adherence to NICE clinical guidelines by fertility clinics

Objective: To evaluate the awareness and response of fertility clinics in the UK to the National Institute for Health and Care Excellence (NICE) guideline recommendation that intrauterine insemination (IUI) should not be offered routinely, in order to report on current practice in the UK. Design: Online questionnaire survey of fertility clinics in the UK regarding their current clinical practice of IUI, formal discussion of the guideline recommendations, and any alterations made since the recommendations. Setting: 66 UK fertility clinics licensed to provide IUI. Participant:s 46 fertility clinics, including 6 clinic groups which represent 70% of all clinics and clinic groups licensed to provide IUI in April 2014 when the survey email was sent. Results: Of the 46 clinics that responded, 96% (44/46) of clinics continue to offer IUI. 98% (43/44) of those offering IUI also use ovarian stimulation. The most commonly used medications for ovarian stimulation are gonadotrophins (95%), followed ...

目标：评估英国生育诊所对国家卫生与保健卓越研究所（National Institute for Health and Care Excellence, NICE）指南建议的认知与回应——该指南建议不应常规提供宫腔内人工授精（intrauterine insemination, IUI）——旨在报告英国当前的临床实践。
设计：针对英国生育诊所开展在线问卷调查，内容涵盖其当前IUI临床实践、对指南建议的正式讨论及建议发布后的任何变更。
研究场景：66家获得IUI服务许可的英国生育诊所。
研究对象：46家生育诊所，其中包括6个诊所集团；在2014年4月（调查邮件发送时），这些集团占所有获得IUI服务许可的诊所及诊所集团的70%。
结果：在46家回应的诊所中，96%（44/46）仍在提供IUI服务。其中98%（43/44）的IUI服务提供者同时采用卵巢刺激疗法。卵巢刺激最常用的药物为促性腺激素（95%），其次为……