De Bragança et al. Cell Reports 2023 (2/2)

These datasets correspond to the publication: De Bragança et al. "APLF and long non-coding RNA NIHCOLE promote stable DNA synapsis in non-homologous end joining" ---- Fig5.zip branched DNA (71G) + Ku + APLF + NIHCOLE branched DNA (71G) + Ku + X4-LIG4 + APLF + NIHCOLE branched DNA (71G) + Ku + APLF + asNIHCOLE branched DNA (71G) + Ku + X4-LIG4 + APLF + asNIHCOLE Fig6.zip branched DNA (71G) + Ku + APLF + SM2 branched DNA (71G) + Ku + X4-LIG4 + APLF + SM2 branched DNA (71G) + Ku + APLF + SM3 branched DNA (71G) + Ku + X4-LIG4 + APLF + SM3 FigS4.zip branched DNA (71G) branched DNA (71G) + APLF unbranched DNA (71D) + Ku + X4-LIG4 + APLF branched DNA (71G) + NIHCOLE branched DNA (71G) + Ku + NIHCOLE branched DNA (71G) + Ku + X4-LIG4 + NIHCOLE unbranched DNA (71D) + Ku + X4-LIG4 + APLF + NIHCOLE FigS5.zip unbranched DNA (71D) + 0.5 nM Ku unbranched DNA (71D) + 1 nM Ku unbranched DNA (71D) + 2 nM Ku unbranched DNA (71D) + 5 nM Ku unbranched DNA (71D) + 10 nM Ku FigS7.zip branched DNA (71G) + Ku + APLF - assay with longer steps

本数据集对应发表文献：De Bragança 等人题为《APLF与长链非编码RNA（long non-coding RNA）NIHCOLE促进非同源末端连接（non-homologous end joining）中的稳定DNA突触形成》的研究。
Fig5.zip 包含以下实验组：
1. 分支DNA（71G）+ Ku + APLF + NIHCOLE
2. 分支DNA（71G）+ Ku + X4-LIG4 + APLF + NIHCOLE
3. 分支DNA（71G）+ Ku + APLF + asNIHCOLE
4. 分支DNA（71G）+ Ku + X4-LIG4 + APLF + asNIHCOLE
Fig6.zip 包含以下实验组：
1. 分支DNA（71G）+ Ku + APLF + SM2
2. 分支DNA（71G）+ Ku + X4-LIG4 + APLF + SM2
3. 分支DNA（71G）+ Ku + APLF + SM3
4. 分支DNA（71G）+ Ku + X4-LIG4 + APLF + SM3
FigS4.zip 包含以下实验组：
1. 分支DNA（71G）
2. 分支DNA（71G）+ APLF
3. 非分支DNA（71D）+ Ku + X4-LIG4 + APLF
4. 分支DNA（71G）+ NIHCOLE
5. 分支DNA（71G）+ Ku + NIHCOLE
6. 分支DNA（71G）+ Ku + X4-LIG4 + NIHCOLE
7. 非分支DNA（71D）+ Ku + X4-LIG4 + APLF + NIHCOLE
FigS5.zip 包含以下实验组：
1. 非分支DNA（71D）+ 0.5 nM Ku
2. 非分支DNA（71D）+ 1 nM Ku
3. 非分支DNA（71D）+ 2 nM Ku
4. 非分支DNA（71D）+ 5 nM Ku
5. 非分支DNA（71D）+ 10 nM Ku
FigS7.zip 包含实验组：分支DNA（71G）+ Ku + APLF — 采用延长孵育步骤的实验