Ivermectin and the soil microbiome

Ivermectin is a commonly-used parasiticide to control livestock nematodes and arthropods (Campbell et al., 1983). Treated animals faecally excrete at least 80% of the drug, and these residues have adverse effects on non-target insects dwelling in dung. However, its effect on soil organisms beneath the dung, particularly soil microorganisms, has scarcely been studied because ivermectin was believed to have no antibacterial or antifungal properties.

伊维菌素（Ivermectin）是一种常用的驱虫剂，用于防控家畜的线虫与节肢动物（Campbell等，1983）。经给药处理的家畜会通过粪便排出至少80%的药物，这些药物残留会对栖息于牲畜粪便中的非靶标昆虫产生不利影响。然而，由于此前认为伊维菌素不具备抗菌或抗真菌活性，其对粪便下方土壤生物——尤其是土壤微生物——的影响几乎未被研究。