Downstream targets up-regulated by oncogenic KRAS with proteomic analysis.

Accession, gene bank accession number; Map, chromosome locus; MOCK, mock-transduced NHBE-T; G12, wild-type KRAS-transduced NHEB-T; V12, oncogenic mutant KRAS-transduced NHBE-T.Proteins whose signal intensities were more than 2-fold higher in KRAS/V12 cells than in mock- and/or KRAS/G12 cells are extracted from our date of a comprehensive proteomic analysis previously described [8]. The proteins sorted are listed in this table.Downstream targets up-regulated by oncogenic KRAS with proteomic analysis.

术语说明：登录号（Accession）：基因库登录号；图谱（Map）：染色体位点；MOCK：空载转导的NHBE-T细胞；G12：野生型KRAS基因转导的NHEB-T细胞；V12：致瘤突变型KRAS基因转导的NHBE-T细胞。本研究从已发表的全面蛋白质组学分析数据[8]中，提取出KRAS/V12细胞中信号强度较MOCK组和/或KRAS/G12组高2倍以上的蛋白质。本表格收录了经筛选的此类蛋白质。本数据集为经蛋白质组学分析鉴定的、受致瘤KRAS基因上调的下游靶标。