Whole genome sequecing of Candida albicans ketoconazole tolerant mutants

C. albicans reference strain SC5314 was exposed to inhibitory concentration of ketoconzole. Seven mutants which obtained tolerance to ketoconazole were karyotyped by whole genome sequencing.

将白色念珠菌（Candida albicans）参考菌株SC5314暴露于酮康唑（ketoconazole）的抑制浓度环境中，共获得7株对该药物产生耐受性的突变株，并通过全基因组测序对其进行核型分析。