Additional file 2 of Mesenchymal stem cells combined with autocrosslinked hyaluronic acid improve mouse ovarian function by activating the PI3K-AKT pathway in a paracrine manner
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Additional file 2: Table S1. Differential expression genes between control and HA-pretreated UC-MSCs. Table S2. Fertility test results of VCD induced-POI mice after MSC combined with HA transplantation. Table S3. Differential expression cytokines between MSC-CM and Fib-CM. Table S4. KEGG pathways analysis of differential cytokines between MSC-CM and Fib-CM. Table S5. Twenty two up-regulated cytokines in MSC-CM related with the PI3K-AKT pathway. Table S6. Differential expression cytokines between MSC-CM and MSC-CM after HA pretreated. Table S7. KEGG pathways analysis of differential cytokines between MSC-CM and MSC-CM after HA pretreated. Table S8. Fertility test results of aged mice after MSC combined with HA transplantation.
附加文件2:表S1。对照组与透明质酸(HA)预处理的脐带间充质干细胞(UC-MSCs)之间的差异表达基因。
表S2。4-乙烯基环己烯二环氧化物(VCD)诱导的早发性卵巢功能不全(POI)小鼠接受间充质干细胞联合透明质酸移植后的生育力检测结果。
表S3。间充质干细胞条件培养液(MSC-CM)与成纤维细胞条件培养液(Fib-CM)之间的差异表达细胞因子。
表S4。间充质干细胞条件培养液与成纤维细胞条件培养液差异细胞因子的KEGG通路分析。
表S5。间充质干细胞条件培养液中22种与PI3K-AKT通路相关的上调细胞因子。
表S6。透明质酸预处理前后的间充质干细胞条件培养液之间的差异表达细胞因子。
表S7。透明质酸预处理后的间充质干细胞条件培养液与原间充质干细胞条件培养液之间差异细胞因子的KEGG通路分析。
表S8。间充质干细胞联合透明质酸移植后老年小鼠的生育力检测结果。
提供机构:
Liu, Qiang; Mi, Xin; Jiao, Wenlin; Liu, Ran; Qin, Yingying; Chen, Zi-Jiang; Zhao, Shidou; Yang, Yajuan; Yan, Tao
创建时间:
2022-02-03



