Results of multicollinearity analysis.

BackgroundAsthma (AS) and chronic obstructive pulmonary disease (COPD) are prevalent chronic airway disorders with shared inflammatory pathways. Considering the systemic inflammatory nature of psoriasis, this study utilized the National Health Interview Survey (NHIS) to investigate its potential association with COPD and AS.MethodsData from the 2023 NHIS were analyzed, with participants selected based on specific inclusion criteria. A baseline table was constructed, and multivariate logistic regression models, along with risk stratification analysis, were employed to examine the correlations between psoriasis and COPD and AS. Receiver operating characteristic (ROC) analysis was conducted to assess the predictive value for both conditions.ResultsA total of 27,106 participants were included in the study. Significant differences were observed in the baseline characteristics of psoriasis, age, race, region, gender, education, marital status, employment, income, smoking habits, health status, mental health, disability, heart attack history, BMI, prediabetes, cancer, hypertension, hypercholesterolemia, arthritis, coronary heart disease, stroke, health insurance, anxiety, and depression (P P P P P P P ConclusionPsoriasis was identified to have a strong association with COPD and AS, which provided valuable insights into understanding the pathogenesis of these diseases.

背景 哮喘（Asthma, AS）与慢性阻塞性肺疾病（Chronic Obstructive Pulmonary Disease, COPD）均为高发慢性气道疾病，二者共享炎症通路。鉴于银屑病具有全身性炎症属性，本研究利用全国健康访谈调查（National Health Interview Survey, NHIS）数据，探讨银屑病与COPD及AS的潜在关联。
方法 本研究对2023年NHIS数据展开分析，依据特定纳入标准筛选研究对象。构建基线特征表，采用多因素logistic回归模型联合风险分层分析，考察银屑病与COPD、AS的相关性；同时实施受试者工作特征（Receiver Operating Characteristic, ROC）分析，以评估其对两种疾病的预测价值。
结果 本研究共纳入27106名研究参与者。在银屑病、年龄、种族、地区、性别、教育程度、婚姻状况、就业情况、收入水平、吸烟习惯、健康状况、心理健康状态、残疾史、心肌梗死病史、BMI、糖尿病前期、癌症、高血压、高胆固醇血症、关节炎、冠心病、脑卒中、医疗保险、焦虑及抑郁等基线特征方面，均观测到显著差异（原文此处重复标注P值，为P P P P P P P）。
结论 本研究证实银屑病与COPD及AS存在显著关联，该发现为深入理解此类疾病的发病机制提供了宝贵的研究视角。