Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-(1,2-anhydro-carba-glucosamine)

Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-(1,2-anhydro-carba-glucosamine) Descriptor: (1~{S},2~{R},3~{R},4~{R},6~{S})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, ACETATE ION, Glycosyl hydrolase family 71, ... Authors: Sobala, L.F, Lu, D, Zhu, S, Bernardo-Seisdedos, G, Millet, O, Zhang, Y, Sollogoub, M, Jimenez-Barbero, J, Davies, G.J. Deposit date: 2018-09-12 Release date: 2018-09-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.27 Å) Cite: From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-alpha-mannosidase. Org.Lett., 20, 2018

溶木聚糖拟杆菌（Bacteroides xylanisolvens）来源的GH99家族内切α-甘露聚糖酶与α-葡萄糖基-1,3-(1,2-脱水碳杂葡萄糖胺)复合物的晶体结构。配体描述：(1S,2R,3R,4R,6S)-4-(羟甲基)-7-氮杂双环[4.1.0]庚烷-2,3-二醇、乙酸根离子、糖苷水解酶家族71（Glycosyl hydrolase family 71）…… 作者：Sobala L.F.、Lu D.、Zhu S.、Bernardo-Seisdedos G.、Millet O.、Zhang Y.、Sollogoub M.、Jimenez-Barbero J.、Davies G.J.。沉积日期：2018-09-12；发布日期：2018-09-26；最后修改日期：2024-01-24。实验方法：X射线衍射（分辨率1.27 Å）。引用文献：《从1,4-二糖到1,3-糖苷碳杂糖：GH99家族内切α-甘露糖苷酶定制抑制剂的合成》，《有机化学通讯》（Org.Lett.），2018年，第20卷。