ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets (drug matrix dataset)

This data was generated by Ganter B, Snyder RD, Halbert DN, Lee MD. Toxicogenomics in drug discovery and development: mechanistic analysis of compound/class-dependent effects using the DrugMatrix database. Pharmacogenomics [Internet]. 2006 Oct;7(7):1025–1044. Available from: http://dx.doi.org/10.2217/14622416.7.7.1025 PMID: 17054413. The data have been curated and analyzed using our open-source R package, ToxicoGx (cran.r-project.org/web/packages/ToxicoGx) and are available publicly in the ToxicoDB web application (www.toxicodb.ca).

本数据集由Ganter B、Snyder RD、Halbert DN、Lee MD生成。相关研究论文题为《药物发现与开发中的毒理基因组学（Toxicogenomics）：基于DrugMatrix数据库的化合物/类别依赖性效应机制分析》，发表于《药物基因组学（Pharmacogenomics）》[互联网]，2006年10月，第7卷第7期，页码范围1025至1044，可通过以下链接获取：http://dx.doi.org/10.2217/14622416.7.7.1025，PMID：17054413。本数据集已通过开源R包ToxicoGx（cran.r-project.org/web/packages/ToxicoGx）完成整理与分析，并可通过ToxicoDB网页应用（www.toxicodb.ca）公开获取。