Examples of top cerebellar eGWAS cisSNP/transcript associations.

There are 2,980 cerebellar cisSNP/transcript associations with qcisSNP/transcript pair is selected for depiction. The chromosome (CHR), SNP, Probe, Gene Symbol (SYMBOL) of these associations are depicted. The uncorrected (P), Bonferroni-corrected (PBonf) P, q values, and Beta coefficients of association are shown for the Non–ADs, ADs and combined (All) analyses. Regression coefficients are based on the SNP minor allele using an additive model.

本数据集共包含2980条小脑顺式SNP (cisSNP)/转录本关联，其中经q值筛选的cisSNP/转录本对被选为本次描述对象。本次描述涵盖这些关联的染色体（CHR）、单核苷酸多态性 (SNP)、探针（Probe）以及基因符号（SYMBOL）信息。同时展示了非阿尔茨海默病组（Non-ADs）、阿尔茨海默病组（ADs）与合并组（All）的分析结果，包括未校正P值（P）、邦费罗尼校正P值（PBonf）、q值以及关联的β系数。回归系数以SNP次要等位基因为基础，通过加性模型计算得到。