Additional file 14 of Transcriptomic analysis of paternal behaviors in prairie voles

Additional file 14. Functional enrichment of genes differentially expressed in the medial preoptic area (MPOA), the nucleus accumbens (NAc), or the lateral septum (LS). For each pairwise comparison, the functional enrichments in gene ontologies of the biological processes (BP), cellular components (CC), and molecular functions (MF) categories as well as in pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) were tested for the differentially expressed genes up- or down-regulated (UP, and DOWN, respectively). The labels of pairwise comparisons were coded in two letters: the first one represents the phenotype (M: mothers, F: fathers, P: paternal males, A: attackers), whereas the second one represents the structure (L: LS). For instance, PLvAL refers to the comparison between the Paternal and Attackers phenotypes in the LS.

补充文件14：内侧视前区（medial preoptic area, MPOA）、伏隔核（nucleus accumbens, NAc）或外侧隔核（lateral septum, LS）中差异表达基因的功能富集分析。针对每一组两两比较，分别针对上调（UP）与下调（DOWN）的差异表达基因，对其所属生物过程（biological processes, BP）、细胞组分（cellular components, CC）、分子功能（molecular functions, MF）三类基因本体（Gene Ontology, GO）条目以及京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）通路开展功能富集检验。两两比较的标签采用双字母编码规则：首字母代表表型类型（M：母鼠，F：父鼠，P：父本雄性鼠，A：攻击鼠），次字母代表检测脑区（L：外侧隔核LS）。例如，PLvAL指代外侧隔核脑区中父本雄性鼠与攻击鼠表型的组间比较。