Hepatitis B capsid Y132A mutant with compound AB-506
收藏Protein Data Bank Japan2024-10-09 更新2026-04-19 收录
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Hepatitis B capsid Y132A mutant with compound AB-506 Descriptor: (1-methyl-1H-1,2,4-triazol-3-yl)methyl {(1S)-4-[(3-chloro-4-fluorophenyl)carbamoyl]-7-fluoro-2,3-dihydro-1H-inden-1-yl}carbamate, 1,2-ETHANEDIOL, Capsid protein Authors: Horanyi, P.S, Mayclin, S.J. Deposit date: 2023-02-28 Release date: 2023-09-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506. Bioorg.Med.Chem.Lett., 94, 2023
创建时间:
2023-02-28



