HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b
收藏Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3gnv
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HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b Descriptor: (11R)-10-acetyl-11-[4-(benzyloxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one, GLYCEROL, RNA-directed RNA polymerase Authors: De Bondt, H, Nyanguile, O. Deposit date: 2009-03-18 Release date: 2009-10-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J.Med.Chem., 52, 2009
创建时间：
2009-03-18
