Chemoselective Synthesis of Polycyclic Spiroindolines and Polysubstituted Pyrroles via the Domino Reaction of 2‑Isocyanoethylindoles
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https://figshare.com/articles/dataset/Chemoselective_Synthesis_of_Polycyclic_Spiroindolines_and_Polysubstituted_Pyrroles_via_the_Domino_Reaction_of_2_Isocyanoethylindoles/2253373
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资源简介：
Chemoselective
2-isocyanoethylindole-based domino reactions for
the construction of polycyclic spiroindoline derivatives and polysubstituted
pyrroles have been developed. The reaction of 2-isocyanoethylindoles
and gem-diactivated olefins lead to the polycyclic
spiroindoline derivatives (up to 92% yields) in EtOH under reflux
conditions. Furthermore, the three-component reaction of 2-isocyanoethylindoles
with gem-diactivated olefins and secondary amines
afford polysubstituted pyrroles (in moderate yields) in CH3CN under reflux conditions.
创建时间：
2016-02-16
