Estimating the predictive power of variables using the area under a receiver operating characteristic curve (AUC).

The p value indicates asymptotic significance with the null hypothesis being that the true AUC is equal to 0.5. The far-right column shows whether the variable is elevated or decreased in autistic patients (ASD) compared to healthy controls. PC1: first principal component in a principal component analysis used as a multivariate biomarker profile. The number of individual biomarkers used in each profile is indicated. The 9 biomarkers (K, Na, LDH, GLTN, GST, CK, CoQ10, Cas7, and MLTN); 7 biomarkers (K, Na, LDH, GSH, CK, CoQ10, and MLTN); 5 ratios (K:Na, GST:GLTN, CK:Cas7, CoQ10: Cas7, and Cas7:MLTN); 9 biomarkers and 5 ratios; or K, GST, and Cas7.