The top four networks generated by the Ingenuity IPA software (allowing only direct connections between proteins/genes).

The results of the network analysis included our genome-wide significant finding (DUSP10) within the top scoring network. P38 MAPK which interacts with DUSP10 is included in the second top network. Also the MHC class II complex is part of the second network. Genes within ours (P38 MAPK and DUSP10) and previously identified genome-wide significant regions are marked in italic, bold text. Only bold text show genes involved in amoebiasis. Underlined genes showed differences in our gene expression analysis (Table 9).Rank; Top functions; Ingenuity score; Number of focus molecules; Molecules in Network.