基于柔性自组装低复杂蛋白质片段可用于调节仿生矿化界面的数据集
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A0028.202307.81.V1.0
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资源简介:
数据集中的数据为基于柔性自组装低复杂蛋白质片段可用于调节仿生矿化界面的数据集,共包含jpg格式图片6张。包括磷酸化和膦酸化无序低复杂性蛋白质片段(LCPS)37SYSGYS42 的自组装形貌,二级结构,体外矿化和受损牙釉质修复,生物相容性,抗细菌黏附性能以及促进成 骨细胞分化的各类表征数据。图1 是LCPSs的表征和它们的自组装。图2 是磷酸化和膦酸化LCPS肽介导的矿化演变。图3 是磷酸化磷化的LCPS肽组装体的体外矿化。图4 是通过LCPS对脱矿牙釉质进行再矿化和修复。图5 是涂敷LCPS后牙釉质的抗细菌黏附表征。图6 是用LCPSs处理的MC3T3-E1细胞的成骨分化活性和转录组测序分析
The dataset contains data on flexible self-assembled low-complexity protein fragments used to regulate biomimetic mineralization interfaces, including 6 images in JPEG format. These images cover various characterization data of phosphorylated and phosphonated disordered low-complexity protein segments (LCPS) 37SYSGYS42, such as self-assembly morphology, secondary structure, in vitro mineralization, damaged enamel repair, biocompatibility, antibacterial adhesion properties, and promotion of osteoblast differentiation. Figure 1 shows the characterization and self-assembly of LCPSs. Figure 2 depicts the phosphorylated and phosphonated LCPS peptide-mediated mineralization evolution. Figure 3 presents the in vitro mineralization of phosphorylated and phosphonated LCPS peptide assemblies. Figure 4 illustrates the remineralization and repair of demineralized enamel via LCPSs. Figure 5 shows the antibacterial adhesion characterization of enamel coated with LCPSs. Figure 6 displays the osteogenic differentiation activity and transcriptome sequencing analysis of MC3T3-E1 cells treated with LCPSs.
提供机构:
北京大学
创建时间:
2024-11-17



