The supplementary material of datasets generated and analyzed during the current study.

Supplementary Material S1: The primer sequences.Supplementary Material S1: The primer sequences.Supplementary Material S2: Summary of transcriptome sequencing data, transcriptome assembly, and functional annotation of unigenes.Supplementary Material S3: Analysis of unigenes differential expression and a summary table of the data. Corresponding to the data of Fig. 2 E–R.Supplementary Material S4: GO annotations analysis of DEGs. Corresponding to the data of Fig. 3 C–D.Supplementary Material S5: EggNOG annotations analysis of DEGs. Corresponding to the data of Fig. 3. E–F.Supplementary Material S6: KEGG enrichment analysis of candidate genes for the expression of recombinant protein in cells. Corresponding to the data of Fig. 3. I–N.Supplementary Material S7: The candidate genes for recombinant protein expression in the KEGG enrichment pathway. Corresponding to the data of Fig. 3 I–N.Supplementary Material S8: KEGG enrichment analysis on exclusive DEGs at individual time points within cells. Corresponding to the data of Fig. 3 Q–V.Supplementary Material S9: The exclusive DEGs for recombinant protein expression in the KEGG enrichment pathway. Corresponding to the data of Fig. 3 Q–V.Supplementary Material S10: Annotation information of selected genes in PCR experiment. Corresponding to the information of Fig. 4.