Comparison intravenous and intranasal dexmedetomidine on emergence recovery and hemodynamics in children undergoing adenotonsillectomy: a randomized clinical trial

Dexmedetomidine is widely used for procedural sedation in children and effectively prevents emergence delirium. However, intravenous dexmedetomidine may lead to hemodynamic instability and delayed recovery. Intranasal dexmedetomidine has been proposed to reduce these side effects. This study compared the effects of intranasal versus intravenous dexmedetomidine on recovery and hemodynamics in children undergoing adenotonsillectomy. The results suggest that intranasal administration provides more stable hemodynamics and more prolonged analgesia and sedation compared to intravenous injection.